Cattle Drive Casserole

Servings: 8 Total Time: 1 hr 12 mins Difficulty: Intermediate
A Hearty Comfort Food Casserole
Delicious homemade Cattle Drive Casserole for family meals pinit

Ah, my friend, let me take you on a culinary journey with one of my absolute favorite recipes: the Cattle Drive Casserole! This dish is the epitome of comfort food, combining hearty flavors and textures that remind me of gatherings around the dinner table after a long day. It’s inspired by the rugged spirit of the American West, packed with ingredients that complement each other beautifully. Trust me, once you make this dish, you’ll understand why it’s a crowd-pleaser!

Why you’ll love this recipe

Picture this: a creamy, cheesy casserole with a warm, flaky biscuit base that cradles a spicy, savory filling. The Cattle Drive Casserole is not just a meal; it’s an experience! The blend of taco seasoning, fresh peppers, and creamy layers give it a soul-soothing quality that’s hard to resist. It’s like wrapping yourself in a warm blanket on a chilly evening.

Not only is it bursting with flavor, but it’s also incredibly versatile—perfect for a family dinner, potlucks, or even just a cozy night in. The leftovers? They somehow taste even better after a night in the fridge, making it a fantastic option for meal prep. Plus, you can easily tweak the ingredients based on what you have on hand, allowing your creativity to shine.

Gather these ingredients

Let’s dive into what you’ll need to make this culinary masterpiece!

  • Large skillet: Essential for browning that lean ground beef to perfection.
  • 2 Medium mixing bowls: One for the biscuit mix and another for the creamy layer.
  • 9 x 13″ casserole dish: The perfect size to hold all that deliciousness.

Ingredients

  • 1.5 pounds Lean Ground Beef: This is your protein base. You can also use ground turkey or chicken if you’re looking for a lighter option.
  • 1 Red Bell Pepper, seeded and chopped: Adds sweetness and a beautiful pop of color. Feel free to swap in other bell peppers if you have them.
  • 1 Yellow Onion, chopped: For added depth. You can go for red onion if you prefer a milder flavor.
  • 1 ounce Taco Seasoning Mix: This spice blend is the heart of the flavor. You can make your own if you’re feeling adventurous or adjust the heat level by choosing mild or spicy.
  • 2 ½ cups Biscuit Mix: You’ll want something like Bisquick. This serves as your comforting base.
  • 1 cup Water: Just enough to bring your biscuit mix together.
  • Cooking Spray (like Pam): A quick spritz to ensure nothing sticks.
  • ½ cup Sour Cream: This rich ingredient lends creaminess and balances the spice.
  • ½ cup Mayonnaise: Adds another layer of richness—you won’t even notice it’s there!
  • 4 ounces Diced Green Chiles, drained: These little green gems add a kick without being overpowering.
  • 1 ½ cups Cheddar Cheese, Fiesta Blend, shredded, divided: The cheesy goodness that brings it all together!
  • 1 teaspoon Garlic Powder: For a hint of savory depth—don’t skip this!
  • ½ cup Salsa, mild: For that southwestern flair. You can use any variety—hot or chunky salsa works well, too.

Step-by-step instructions overview

Ready to whip up this delightful dish? Let’s get cooking!

  1. Preheat the oven: Set it to 350℉ so it’s hot and ready.
  2. Cook the ground beef: Heat a large skillet over medium-high heat. Load in the ground beef, breaking it apart with your spoon. Cook until no longer pink, then drain the excess fat. (While the beef cooks, prepare the biscuit dough!)
  3. Prepare the biscuit dough: In a mixing bowl, stir together the biscuit mix and water. Don’t be shy—use your hands for a lovely, cohesive dough. Lightly spray your casserole dish with cooking spray, then press the dough into it, spreading it to the edges. Bake for 5-8 minutes until it’s just set and golden. Remove and keep the oven on.
  4. Cook the veggies: Toss in the chopped onions and peppers with the beef. Stir and cook for about 4 minutes, then mix in that taco seasoning and remove from heat.
  5. Assemble the layers: Evenly spread the beef mixture over your baked biscuit layer.
  6. Prepare the sour cream layer: In another bowl, combine sour cream, mayonnaise, drained green chiles, ¾ cup of shredded cheese, and garlic powder. Mix until it’s smooth and creamy, then carefully spread this mix over the beef.
  7. Add salsa and cheese: Drop spoonfuls of salsa over the sour cream layer without spreading, then sprinkle the remaining cheese on top.
  8. Bake: Slide the casserole back into the oven uncovered. Bake for 30 minutes or until it’s hot and bubbly.

Best way to enjoy it

Now comes the fun part—serving! This casserole is fantastic on its own, but if you want to elevate it a notch, here are a few suggestions:

  • Serve it with a simple side salad tossed in vinaigrette to balance the richness.
  • Add sliced avocados and a dollop of sour cream on top for extra creaminess.
  • If you like things spicy, fresh jalapeños or hot sauce on the side will give it that extra kick.

Storage and reheating tips

Got leftovers? You’re in luck! This casserole stores beautifully. Let it cool to room temperature, then cover it tightly with foil or transfer it to an airtight container. It can be kept in the fridge for about 3-4 days. For longer storage, you can freeze it for up to 3 months. Just reheat it in the oven; it doesn’t have to be perfect—those bubbly edges will be shouting "comfort food!"

Helpful cooking tips

Here’s a few pro tips to ensure your casserole turns out perfectly:

  • Choose quality beef: Lean ground beef gives you the best flavor without all the grease. If you’re using a fattier cut, be sure to drain it well.
  • Don’t rush the veggie cooking: Sautéing the peppers and onions with the beef really amplifies their flavors.
  • Customize your layers: Feel free to add black beans or corn to the beef mixture for extra nutrition.
  • Garnish generously: Fresh cilantro or green onions on top before serving add a fresh flavor and a pop of color.

Creative Twists

Let your creativity run wild with this recipe! Here are some fun variations:

  • Chili cheese style: Stir in some kidney beans and top with Fritos for a fun crunch.
  • Different proteins: Use shredded chicken or even tofu for a vegetarian option!
  • Herb it up: Fresh cilantro or lime juice in your sour cream layer for a twist of zest.
  • Gluten-free version: Look for gluten-free biscuit mixes to cater to specific diets.

Your Cattle Drive Casserole is more than just a recipe; it’s an invitation to create, share, and enjoy! So roll up your sleeves, embrace the flavors, and make it your own. I hope you’ll come back and share your experiences—did you add a twist? What did your family think? Let’s keep the conversation going and inspire each other in the kitchen!

Difficulty: Intermediate Prep Time 20 mins Cook Time 45 mins Rest Time 7 mins Total Time 1 hr 12 mins
Cooking Temp: 350  F Servings: 8 Estimated Cost: $ 15 Calories: 450
Best Season: Suitable throughout the year

Description

Experience the warmth of the American West with the Cattle Drive Casserole, a flavorful blend of ground beef, veggies, and cheesy goodness atop a biscuit base.

Ingredients

Main Ingredients

Instructions

Cooking Steps

  1. Preheat the oven

    Set it to 350°F.
  2. Cook the ground beef

    Heat a large skillet over medium-high heat, cook the ground beef until no longer pink, and drain excess fat.
    Prepare the biscuit dough while beef cooks.
  3. Prepare the biscuit dough

    Mix biscuit mix and water, then press the dough into a greased casserole dish. Bake for 5-8 minutes.
    Dough should be set and golden.
  4. Cook the veggies

    Add onions and peppers to the beef, cook for about 4 minutes, then mix in taco seasoning.
    Remove from heat afterwards.
  5. Assemble the layers

    Spread the beef mixture evenly over the biscuit layer.
  6. Prepare the sour cream layer

    Mix sour cream, mayonnaise, green chiles, cheese, and garlic powder. Spread over the beef.
  7. Add salsa and cheese

    Drop spoonfuls of salsa over the sour cream layer and sprinkle remaining cheese on top.
  8. Bake the casserole

    Place the casserole in the oven and bake for 30 minutes until hot and bubbly.

Nutrition Facts

Servings 8


Amount Per Serving
Calories 450kcal
% Daily Value *
Total Fat 30g47%
Saturated Fat 12g60%
Trans Fat 1g
Cholesterol 85mg29%
Sodium 800mg34%
Potassium 600mg18%
Total Carbohydrate 35g12%
Dietary Fiber 2g8%
Sugars 2g
Protein 25g50%

Vitamin A 800 IU
Vitamin C 30 mg
Calcium 300 mg
Iron 3.5 mg

* Percent Daily Values are based on a 2,000 calorie diet. Your daily value may be higher or lower depending on your calorie needs.

Note

Perfect for meal prep and tastes even better as leftovers!
Keywords: casserole, comfort food, beef, cheese, biscuits, easy recipe
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Frequently Asked Questions

Expand All:

Can I freeze leftovers?

Yes, it can be frozen for up to 3 months.

What can I substitute for the beef?

Shredded chicken or even tofu can be used as alternatives.

Irelia Novak Food and Lifestyle Blogger

Hi, I'm Irelia Novak, a passionate home cook and food blogger who loves turning simple ingredients into delicious everyday meals. I live a cozy, family-centered life and enjoy exploring new flavors, discovering fresh ideas, and sharing inspiring recipes. When I’m not in the kitchen, you’ll find me traveling, journaling, or spending quality time with the people I love.

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